| Title: Trifunctional probe for target identification
Contact: Mary O'Reilly
Description: This illustration is on the cover of the September, 2009 issue of the journal Chemistry & Biology to illustrate the article by Xu, et al. “Chemical probes identify a role for histone deacetylase 3 in Friedreich’s ataxia gene silencing” Chem. Biol. 2009, 16, 980-9.
To identify HDAC3 as the inhibitor’s target, a trifunctional chemical probe was used that incorporated the inhibitor, a handle for cross-linking, and a handle for detection.
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| Title: Ow!
Contact: Gail Guth
Description: Illustration for spelling wall cards set, ©Developmental Studies Center (devstu.org). Provides older readers with basic instruction in phoneme awareness, phonics, and sight words. Ink line and colored pencil.
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| Title: Human Heart
Contact: Science Picture Company
Description: A close-up view of the human heart.
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| Title: Human musculature front and back
Contact: Carlyn Iverson
Description: Anatomical illustration, human musculature, front musclulature, back musculature
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| Title: The Exploding Cell
Contact: Elizabeth Morales
Description: A fanciful illustration of the components of the eukaryotic animal cell
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| Title: The Pancreas and Digestive System
Contact: Jane Whitney
Description: Labeled diagram of the pancreas and pancreatic duct and its orientation to other organs inside the body, for a grade 6 textbook.
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| Title: Dumbbell rowing anatomy
Contact: William Hamilton
Description: Female athlete demonstrating dumbbell rowing exercise.
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| Title: Memory Loss
Contact: Travis Vermilye
Description: Editorial Illustration on memory loss and Alzheimer's disease.
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| Title: Simple Machines: Pliers
Contact: Emil Huston
Description: FIRST-CLASS LEVER: McGraw-Hill Grade 4 Science Illustration
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| Title: Supine breast examination
Contact: Pam Little, CMI
Description: Patient placement for supine breast examination
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| Title: anatomy & physiology self portrait
Contact: Steven Melendrez
Description: Facial anatomy showing selective features.
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| Title: HDAC7 inhibitor restores function to CFTR
Contact: Mary O'Reilly
Description: The cystic fibrosis transmembrane conductance regulator is a cell surface chloride channel that works to maintain proper hydration of airway epithelium. Mutation of this channel is implicated in cystic fibrosis, but a small molecule histone deacetylase inhibitor is able to restore function to the mutated channel. Hutt, et al. “Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.” Nature Chem.Biol. 2010, 6, 25-33.
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| Title: Sh-h-h!
Contact: Gail Guth
Description: Illustration for spelling wall cards set, ©Developmental Studies Center (devstu.org). Provides older readers with basic instruction in phoneme awareness, phonics, and sight words. Ink line and colored pencil.
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| Title: Human Gender Comparison
Contact: Diana Marques
Description: Comparison of male (left) and female human skulls from a frontal and side views. Commissioned by the Smithsonian Institution to use on the website of an exhibition of the Natural History Museum
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| Title: Ear
Contact: Jane Whitney
Description: For a grade 8 student text. Shows the balance of air pressure on either side of the ear drum.
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| Title: Sciatica
Contact: William Hamilton
Description: Human vertebral section demonstrating a ruptured disc and pressure on nerve.
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| Title: All the Helpers in the Garden
Contact: MaryBeth Hinrichs
Description: Can you imagine all the helpers in the garden?
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| Title: Sagittal Female Pelvis
Contact: Travis Vermilye
Description: Sagittal Female Pelvis. Carbon Dust
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| Title: Posterior Fixation Lumbar Spine
Contact: Pam Little, CMI
Description: Use of fixation devices to stabilize lumbar spine
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| Title: Phonecian Trireme
Contact: Frank Ippolito
Description: Cover illustration for the New York Times Science Times depicting a restoration of the earliest of these ancient warships.
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| Title: Forensic Sculpture
Contact: Chris Sanders
Description: Working with an anthropologist and the basic anatomy of the facial muscles the sculptures are developed using each individual's unique skeletal traits to reveal the appearance of the person as they would have looked in life. These study models represent closed cases.
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| Title: Unc93b1 escorts three Toll-like receptors
Contact: Mary O'Reilly
Description: Unc93b1 is a multi-spanning transmembrane domain that is responsible for transporting Toll-like receptors 3, 7, and 9 from the endoplasmic reticulum to endosomes, where recognition of self-nucleic acids triggers signaling and autoantibody production.
Kono DH, et al. “Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus”. Proceedings of the National Academy of Sciences, USA 2009, 106, 12061-6.
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| Title: Superficial muscle groups, posterior view
Contact: Pam Little, CMI
Description: Superficial muscles of the upper and lower limbs and back.
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| Title: Back Exercise 1
Contact: Carlyn Iverson
Description: View of an exercise for the back, created digitally.
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| Title: Jumprope
Contact: Gail Guth
Description: Illustration for spelling wall cards set, ©Developmental Studies Center (devstu.org). Provides older readers with basic instruction in phoneme awareness, phonics, and sight words. Ink line and colored pencil.
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| Title: Stretching Positions
Contact: Diana Marques
Description: These and several other images were done to illustrate the muscles involved in different stretching positions and how they affect the human body.
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| Title: Endomembrane System in Eukaryotic Cell
Contact: Elizabeth Morales
Description: The endomembrane system is a group of interrelated organelles such as the endoplasmic reticulum and the golgi apparatus.
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| Title: Maxillofacial surgery skull
Contact: Alison Schroeer
Description: This medical illustration was created by medical illustrator Alison Schroeer of Schroeer Scientific Illustration, as part of a maxillofacial surgery series. It depicts branches of the external carotid artery branching into and near the temporalis muscle.
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| Title: Invitro Fertilization
Contact: Jane Whitney
Description: Illustration for a grade 9 science text book.
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| Title: Anterior view of human cruciate ligaments
Contact: William Hamilton
Description: Anterior view of human cruciate ligaments and related structures.
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| Title: Intestinal Vessels
Contact: Travis Vermilye
Description: Cadaver Sketch of Intestinal Vessels
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| Title: Toll-like receptors in autoimmunity
Contact: Mary O'Reilly
Description: Co-localization of Toll-like receptors 3, 7, and 9 with nucleic acids taken up into endosomes leads to hallmarks of lupus-like systemic autoimmunity, including the production of anti-nucleic acid antibodies.
Kono DH, et al. “Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus”. Proceedings of the National Academy of Sciences, USA 2009, 106, 12061-6.
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| Title: Female Reproductive Anatomy
Contact: Jane Whitney
Description: For a grade 6 human reproduction student text.
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| Title: Chromosomes
Contact: Science Picture Company
Description: A conceptual Image of chromosomes.
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| Title: Structural Proteins and the Cytoskeleton
Contact: Nicolle Rager Fuller
Description: A vast network of interconnected structural proteins permeate the cell, providing structure, order, and transport highways. A few of the cytoskeleton components shown include: actin, tubulin, cadherin, microtubules and transport vesicles carried by dynein.
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| Title: Cross section thorax and abdomen
Contact: Pam Little, CMI
Description: Diagrammatic anatomy of thorax and abdomen in cross section
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| Title: Human skeleton
Contact: Alison Schroeer
Description: This anatomical artwork of the anterior and posterior human skeleton has all bones labeled. This medical illustration was created by medical illustrator Alison Schroeer of Schroeer Scientific Illustration.
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| Title: Time Trialist
Contact: Kim Harrell
Description: The search for speed leads to constant innovation in the time-trial rider's bike, clothing, and riding technique.
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| Title: Comparing Chimp-human Supralaryngeal Airway
Contact: Gail Guth
Description: Watercolor, colored pencil and digital illustration comparing chimpanzee and human supralaryngeal airways. Created for the textbook "Biological Anthropology: The Natural History of Humankind", by Craig Stanford, John S. Allen, and Susan C. Anton; published by Prentice Hall. Textbook art developed and managed by Precision Graphics, Inc.
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| Title: Tony
Contact: Kathleen McKeehen
Description: Portrait
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| Title: Stem cells for eye from patient’s own skin
Contact: Mary O'Reilly
Description: This illustration was created to accompany a highlight in the Scripps Research Institute News&Views that reported on a finding by Martin Friedlander and colleagues. Adult skin cells may be induced to become stem cells, and then get coaxed into becoming retinal pigmented epithelial cells. The hope is that these cells may then be used for transplantation in the treatment of age-related macular degeneration.
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| Title: Arm muscles, tendons; Leg skeleton, ligaments
Contact: Marjorie Leggitt
Description: Anatomical illustrations prepared for Denver Museum of Nature and Science - Expedition Health exhibit and educational materials
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| Title: Flu Viruses in the Throat
Contact: Dr Jon Heras
Description: Flu viruses in the throat. Computer artwork of influenza (flu) viruses (ovals) in a human throat. The lining of the throat includes cells that are covered in cilia (small hair-like projections). These cilia normally move rhythmically to help expel dust, micro-organisms and other particles. However, a large number of viruses in the throat can prevent the cilia from working properly, allowing the viruses to infect the cells of the throat and lungs.
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| Title: Male Reproductive Anatomy
Contact: Jane Whitney
Description: For a grade 6 human reproduction student text.
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| Title: DNA
Contact: Science Picture Company
Description: An illustration showing three DNA strands
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| Title: Mitochondria and Free Radicals
Contact: Nicolle Rager Fuller
Description: Created for Science News magazine, this illustration shows the free radicals that are formed in the electron transport chain of the mitochondrial ATP generation. These free radicals have been implicated in many diseases.
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| Title: Heart tissue layers
Contact: Carlyn Iverson
Description: The heart is composed of various tissue layers, each with a special function or structure. It is this combination of tissues, whether they be of muscle, connective tissue, or conduction fibers, that provides the heart it's durability and flexibility to pump for many years.
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| Title: Ivory harpoon head
Contact: Katura Reynolds
Description: This harpoon head was carved out of solid ivory. The top flanges that held the spear tip have broken off with time, but the lower hole where the pole was inserted is still clearly visible. There is a detailed pattern of incised circles and dots on the surface of the harpoon head. This image was published in Aleut Art by Lydia T. Black.
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| Title: Girl holding Chickadee
Contact: Denise Wagner
Description: Girl holding Chickadee.
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| Title: Bathing beauty
Contact: William Hamilton
Description: Female athletic torso in grasaille oils.
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| Title: Male Cross Section at L2-L3
Contact: Travis Vermilye
Description: Male cross sectional anatomy at the L2-L3 level. Digital Illustration.
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| Title: The influence of pollution on the environment
Contact: Mieke Roth
Description: I am working on a series of large illustrations for a Dutch governmental institution that is in charge of the maintenance of the waterways in the west of the Netherlands. Over the next 10 years a large project is being conducted in which most of these waterways are deepened.
This detailed illustration is a part the second large illustration of the series, incorporated in several newsletters for the general public. The aim is to inform and to get the public involved in the decision process.
This specific illustration is about what kind of influences normal activities, like spraying the crops, can have on the quality of the ground. This type of activity is accepted, in spite of fact that the same quality sediment from the bottom of a waterway normally results in panic and strict measures to safeguard it from the environment.
As are all the illustrations in this series, this is again a typical Dutch landscape.
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| Title: Human skull
Contact: Alison Schroeer
Description: This medical illustration shows an anterior view of a human skull. This anatomical artwork was created by medical illustrator Alison Schroeer of Schroeer Scientific Illustration to show the bones of the human head.
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| Title: Jaw muscles of Australopithecus robustus
Contact: Gail Guth
Description: Watercolor, colored pencil, and digital illustration of the masticatory muscles of Australopithecus robustus. Illustration created for the textbook "Biological Anthropology: The Natural History of Humankind", by Craig Stanford, John S. Allen, and Susan C. Anton; published by Prentice Hall. Textbook art developed and managed by Precision Graphics, Inc.
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| Title: Colonoscopy
Contact: Pam Little, CMI
Description: Patient education material depiciting colonoscope and colonoscopy procedure.
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| Title: Carbohydrate binding regulates inflammation
Contact: Mary O'Reilly
Description: By binding carbohydrates on adipocytes, the protein Mgl1 on monocytes regulates the recruitment of monocytic precursors of inflammatory macrophages to adipose tissue. This illustration was created for the January, 2010 Functional Glycomics Update (Nature Publishing Group) to accompany a highlight of the paper by Westcott DJ, et al. “MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity.” J Exp Med. 2009, 206, 3143-56.
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| Title: Digestive System
Contact: Marjorie Leggitt
Description: Anatomical classroom charts showing the digestive system. Created for Expedition Health educational in-house and outreach program at the Denver Museum of Nature and Science
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| Title: Pituitary Gland
Contact: Jane Whitney
Description: Simple illustration showing the pituitary gland's location and hormonal influence on the reproductive organs of the pre-adolescent teen.
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| Title: Brain and Skull Wireframe
Contact: Science Picture Company
Description: A side view of the skull and bones for the upper neck, wireframe appearance. The right hemisphere of the brain is also visible within the skull.
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| Title: Cancer Research and Surrogate Endpoints
Contact: Nicolle Rager Fuller
Description: Historically, drug trials judged the efficacy of a new drug by looking at it's ability to cure the given disease. Increasingly, surrogate endpoints are used as gauges for drug value. Examples are shown here for cancer research, including: tumor size, metastasis and cancer cell mobility and tumor antigens in the blood stream. Created for CR magazine,
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| Title: Submuscular Ulnar Nerve Transposition
Contact: Ikumi Kayama
Description: Plate for orthopedic surgery textbook for hand surgeons and residents.
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| Title: Human heart chambers
Contact: Alison Schroeer
Description: This medical illustration of the human heart was created by medical illustrator Alison Schroeer of Schroeer Scientific Illustration. Designed for patient education, it depicts the atriums, ventricles, and valves of the heart in cross-section.
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| Title: Alveoli
Contact: Travis Vermilye
Description: Alveoli of the lung
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| Title: Drug pump placement
Contact: Pam Little, CMI
Description: Placement of drug pump and intraspinal catheter for pain management
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