search tips for the image bank  by text terms:  results as:  per page:  ImagesImages/TextTextContact List 812163264  by category andornot Any CategoryChild/YouthHistoricMedicalNatureScienceTechnicalVeterinary  by subject #1 andornot Any SubjectAnimalBotanicalGeologyAmphibiansAnthropologyArcheologyAstronomy/SpaceBirdsCartographyDinosaursEmbryologyEntomologyFishesHistologyInvertebratesMammalsMarine LifePaleontologyPhysicsReptilesVertebratesAnatomicalDentalHumanMicrobialMicroscopicMolecularPharmaceuticalProductsSurgical  by subject #2 andornot Any SubjectAnimalBotanicalGeologyAmphibiansAnthropologyArcheologyAstronomy/SpaceBirdsCartographyDinosaursEmbryologyEntomologyFishesHistologyInvertebratesMammalsMarine LifePaleontologyPhysicsReptilesVertebratesAnatomicalDentalHumanMicrobialMicroscopicMolecularPharmaceuticalProductsSurgical  by type andornot Any TypeAdvertisingArchitectureCartoonEcosystemEditorialInstitutionalLandscapeLegalProcessesSketchbookStorybookTechnology  by media  andornot Any Media3-D/ExhibitsAnim./MultimediaColorLine/B&WPhotography  by restrictions  andornot All ImagesAvailable OnlyPortfolio Only  by artist andornot Any ArtistAronow, J.Beade, E.Beveridge, M.Damstra, E.Di Cerbo, S.Drummond, S.Fady, K.Fairman, CMI, J.Fierstein, D.Fuller, N.Galvan III, A.Gleave, P.Gralapp, C.Griswold, T.Guth, G.Hamilton, W.Hansen, A.Harmon, B.Harrell, K.Heras, D.Hinrichs, M.Huston, E.Ippolito, F.Ivanyi, R.Iverson, C.Johnson, K.Kayama, I.Krause, S.Kulak, J.Leggitt, M.Little, CMI, P.Litwak, T.Luscombe, M.Marques, D.McKeehen, K.Megahan, J.Melendrez, S.Mikel, G.Morales, E.Nelson, M.Nicholson, T.Norton, J.O'Keefe, L.O'Reilly, M.Petrochko, D.Picture Company, S.Powell, C.Raham, G.Rauh, R.Reynolds, K.Rohner, D.Roth, M.Rothman, M.Sanders, C.Schroeer, A.Schwab, R.Sealing, L.Shaw, C.Smith, B.Sullivan, T.Twiddy, S.Vermilye, T.Wagner, D.Walla, B.Wheeler, R.Whitney, J.     Displaying images 1 to 64 of 87. Search Results For: Cartoon Title: Trifunctional probe for target identification Contact: Mary O'Reilly Description: This illustration is on the cover of the September, 2009 issue of the journal Chemistry & Biology to illustrate the article by Xu, et al. “Chemical probes identify a role for histone deacetylase 3 in Friedreich’s ataxia gene silencing” Chem. Biol. 2009, 16, 980-9. To identify HDAC3 as the inhibitor’s target, a trifunctional chemical probe was used that incorporated the inhibitor, a handle for cross-linking, and a handle for detection. Title: Ow! Contact: Gail Guth Description: Illustration for spelling wall cards set, ©Developmental Studies Center (devstu.org). Provides older readers with basic instruction in phoneme awareness, phonics, and sight words. Ink line and colored pencil. Title: HDAC7 inhibitor restores function to CFTR Contact: Mary O'Reilly Description: The cystic fibrosis transmembrane conductance regulator is a cell surface chloride channel that works to maintain proper hydration of airway epithelium. Mutation of this channel is implicated in cystic fibrosis, but a small molecule histone deacetylase inhibitor is able to restore function to the mutated channel. Hutt, et al. “Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.” Nature Chem.Biol. 2010, 6, 25-33. Title: Sh-h-h! Contact: Gail Guth Description: Illustration for spelling wall cards set, ©Developmental Studies Center (devstu.org). Provides older readers with basic instruction in phoneme awareness, phonics, and sight words. Ink line and colored pencil. Title: Unc93b1 escorts three Toll-like receptors Contact: Mary O'Reilly Description: Unc93b1 is a multi-spanning transmembrane domain that is responsible for transporting Toll-like receptors 3, 7, and 9 from the endoplasmic reticulum to endosomes, where recognition of self-nucleic acids triggers signaling and autoantibody production. Kono DH, et al. “Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus”. Proceedings of the National Academy of Sciences, USA 2009, 106, 12061-6. Title: Jumprope Contact: Gail Guth Description: Illustration for spelling wall cards set, ©Developmental Studies Center (devstu.org). Provides older readers with basic instruction in phoneme awareness, phonics, and sight words. Ink line and colored pencil. Title: Cartoon Crow Contact: Denise Wagner Description: Computer painting of a crow. Title: Toll-like receptors in autoimmunity Contact: Mary O'Reilly Description: Co-localization of Toll-like receptors 3, 7, and 9 with nucleic acids taken up into endosomes leads to hallmarks of lupus-like systemic autoimmunity, including the production of anti-nucleic acid antibodies. Kono DH, et al. “Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus”. Proceedings of the National Academy of Sciences, USA 2009, 106, 12061-6. Title: Stem cells for eye from patient’s own skin Contact: Mary O'Reilly Description: This illustration was created to accompany a highlight in the Scripps Research Institute News&Views that reported on a finding by Martin Friedlander and colleagues. Adult skin cells may be induced to become stem cells, and then get coaxed into becoming retinal pigmented epithelial cells. The hope is that these cells may then be used for transplantation in the treatment of age-related macular degeneration. Title: Carbohydrate binding regulates inflammation Contact: Mary O'Reilly Description: By binding carbohydrates on adipocytes, the protein Mgl1 on monocytes regulates the recruitment of monocytic precursors of inflammatory macrophages to adipose tissue. This illustration was created for the January, 2010 Functional Glycomics Update (Nature Publishing Group) to accompany a highlight of the paper by Westcott DJ, et al. “MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity.” J Exp Med. 2009, 206, 3143-56. Title: Homophilic binding regulates apoptosis Contact: Mary O'Reilly Description: PECAM is a glycoprotein that binds to glycans on other copies of PECAM on the same or other cells, regulating apoptosis. This illustration was created for the February, 2010 Functional Glycomics Update (Nature Publishing Group) to accompany a highlight of the paper by Kitazume S, et al. “{alpha}2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.” J Biol Chem. 2010 285, 6515-21. Title: Small molecules for stem cell research Contact: Mary O'Reilly Description: This promotional poster was created for an R&D firm to highlight small molecule reagents for use in stem cell research. Title: Carbohydrate degradation acidifies endosome Contact: Mary O'Reilly Description: When nitric oxide reacts with certain engulfed bacterial polysaccharides in cellular endosomes, proton byproducts lower the pH, leading to downstream effects on innate and adaptive immune responses. This illustration was created to accompany a highlight for the April, 2010 Functional Glycomics Update (Nature) that describes the article by Lewis, CJ. and Cobb, BA. "Carbohydrate oxidation acidifies endosomes, regulating antigen processing and TLR9 signaling." J. Immunol. 2010, 184, 3789-800. Title: Chemical capture of candidate ligands Contact: Mary O'Reilly Description: In an effort led by Ramya Chakravarthy in James Paulson’s lab at Scripps, the natural ligands of the glycan-binding protein CD22 were identified using glycoproteomics. This illustration depicts the use of a CD22-Fc chimera to identify a number of candidate ligands by photo-cross-linking. Ramya TN, et al. “In situ trans ligands of CD22 identified by glycan-protein photo-cross-linking enabled proteomics.” Mol. Cell Proteomics, 2010, Feb 19. [Epub ahead of print] Title: Vermiculture Dinner Contact: Julie Kulak Description: A red wiggler ready to dig in to his composting dinner. Yummo! Title: Intercellular Communication Contact: Travis Vermilye Description: An action potential is delivered to a motor neuron triggering an action potential in a muscle cell. This animation is currently on display in the Cincinnati Children's Research Foundation as part of a large sculptural wall in the main entrance. Title: Blocking enzymes can delay fruit ripening Contact: Mary O'Reilly Description: Tomato ripening can be slowed by silencing the genes encoding enzymes that degrade glycans on cell walls. This illustration was created for the February, 2010 Functional Glycomics Update (Nature Publishing Group) to accompany a highlight of the paper by Meli VS, “Enhancement of fruit shelf life by suppressing N-glycan processing enzymes.” Proc Natl Acad Sci U S A, 2010, 107, 2413-8. Title: Vermiculture Bedding Contact: Julie Kulak Description: Cartoon illustration of a worm enjoying his bedding substrate. Title: Fur Angels Need You Contact: MaryBeth Hinrichs Description: Posters of this image were sold to raise funds for projects to benefit homeless families and police dogs in Michigan. Title: Cells, Tissues, Organs Contact: Travis Vermilye Description: A brief overview of embryonic development with focus on generation of the eye. This animation is currently on display in the Cincinnati Children's Research Foundation as part of a large sculptural wall in the main entrance. Title: Spinach E.coli outbreak Contact: Melisa Beveridge Description: Photoshop and Illustrator drawing representing the recent E.coli outbreak from spinach. This is to be published in "Science Notes" online. Title: Brazilian Rain Forest Activity Sheet Contact: Marjorie Leggitt Description: Client: Denver Museum of Nature and Science. Project: teacher guided kids' activity board about the rain forest ecosystem, its flora and fauna. 20" x 14". Computer generated. Title: A2M shields Surfactant Protein D Contact: Mary O'Reilly Description: Surfactant protein D (SPD) is a tetramer of collagen-like triple helices terminating in trimeric lectin domains, which serve to aggregate invading bacteria by binding to carbohydrates on the surface. SPD also binds alpha-2-macroglobulin, which protects SPD from neutralization by proteases. Craig-Barnes, HA., et al. “Surfactant protein D interacts with alpha-2-macroglobulin and increases its innate immune potential” J. Biol. Chem. 2010, March 5 [Epub ahead of print] Title: Surfin' Seafood Cartoon Contact: John Norton Description: T-shirt Design for Aquaculture 2004 Conference in Hawai'i Title: Jade Tree Frog Rhacophorus dulitensis Contact: Melisa Beveridge Description: A Photoshop rendering of a Jade tree frog making a foam nest on a Resak Palm - Vatica yeechongii. Title: snowflakes Contact: Steven Melendrez Description: T-rex and Triceratops Title: Humpback Whale Contact: Theophilus Britt Griswold Description: Color pencil sketch created for museum visitor research. Title: Glycan termination to disrupt cellular functi Contact: Mary O'Reilly Description: Metabolic labeling of leukocytes with a non-natural sugar analog leads to incorporation of this analog into the cell surface, disrupting the synthesis of native glycans involved in leukocyte rolling along endothelial cells. Protein-glycan interactions that support rolling enable leukocytes to reach the site of injury. Marathe DD. et al. "Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins" Blood, 2010, 115, 1303-12. Title: A.D.O.P.T.© Critters Contact: Gail Guth Description: B&W line art for Binder Park Zoo's Valentine's Day adopt program advertising. Title: Targeting B cells with glycans Contact: Mary O'Reilly Description: Claire Chen and Gladys Completo in Jim Paulson’s lab at TSRI have shown that drug-loaded liposomes decorated with the ligand of an endocytic receptor on B cells can bind, and be taken up by, B cells. This strategy has been used to successfuly treat B cell lymphoma in mice. Chen, WC, et al., “In vivo targeting of B cell lymphoma with glycan ligands of CD22”, Blood, 2010, Epub Feb. 24. Title: Members Day Animals Contact: Gail Guth Description: B&W line art for Binder Park Zoo's annual Members Day Picnic advertising. Title: Multivalency in complement cytotoxicity Contact: Mary O'Reilly Description: This image was made for a lecture on multivalency to describe how complement-dependent cytotoxicity uses multivalency on two levels: one to recognize the antigen using a decavalent antibody (IgM), and another to use a hexameric protein complex to recognize the IgM. Following this recognition process, a cascade of proteolytic events leads to lysis of the target cell. Title: Weakfish Within Six-Pack Ring Contact: John Norton Description: Title: Achieving multivalency with beads on a string Contact: Mary O'Reilly Description: This illustration was prepared for a lecture on multivalency, and describes a pseudopolyrotaxane, consisting of several carbohydrate-modified cyclodextrin molecules assembled onto a carbon chain. Positively-charged viologen “speed bumps” on the chain maintain spacing between the cyclodextrins, while allowing rotational and translational degrees of freedom. Belitsky JM, Nelson A, Hernandez JD, Baum LG, Stoddart JF. Multivalent interactions between lectins and supramolecular complexes: Galectin-1 and self-assembled pseudopolyrotaxanes. Chemistry&Biology, 2007, 14, 1140-51. Title: Neutralizing galectins with polyrotaxanes Contact: Mary O'Reilly Description: This illustration was prepared for a lecture on multivalency, and describes how pseudopolyrotaxane with pendant carbohydrate ligands can cross-link and aggregate galectin-1 while occupying its binding site, thus neutralizing a lectin that can play a role in promoting cancer metastasis. Belitsky JM, Nelson A, Hernandez JD, Baum LG, Stoddart JF. Multivalent interactions between lectins and supramolecular complexes: Galectin-1 and self-assembled pseudopolyrotaxanes. Chemistry&Biology, 2007, 14, 1140-51. Title: A key gene for hearing identified Contact: Mary O'Reilly Description: Loxhd1, a multi-domain protein localized to the membrane of the stereocilia in ears, is important for proper hearing. This illustration was created to accompany a highlight in the Scripps Research Institute News&Views on the article by Grillet N, et al. “Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans.” American Journal of Human Genetics, 2009, 85, 328-37. Title: Chemical conjugation of virus surfaces Contact: Mary O'Reilly Description: Published in this highlight: Udit AK, Hackenberger, C.P., O’Reilly, M.K. “Chemically tailored multivalent virus platforms: from drug delivery to catalysis” ChemBioChem, 2010, 11, 481-4. To describe these articles: Wu W., et al. "Genome-free viral capsids as multivalent carriers for taxol delivery"Angew. Chemie Int. Ed. Eng., 2009, 48, 9493-7. Stephanopoulos, N., et al. “Nanoscale integration of sensitizing chromophores and porphyrins with bacteriophage MS2” Angew. Chem. Int. Ed. Engl. 2009, 48, 9498-502. Title: Horseshoe Crab Donating Blood Cartoon Contact: John Norton Description: Horseshoe crab blood is removed from these animals without harming them. This unique blood is used in the testing of the purity of certain vaccines by the pharmaceutical industry. This illustration was used on an interpretive sign centered on horseshoe crabs. Title: Viruses for drug delivery and catalysis Contact: Mary O'Reilly Description: Published in this highlight: Udit AK, Hackenberger, C.P., O’Reilly, M.K. “Chemically tailored multivalent virus platforms: from drug delivery to catalysis” ChemBioChem, 2010, 11, 481-4. To describe these articles: Wu W., et al. "Genome-free viral capsids as multivalent carriers for taxol delivery"Angew. Chemie Int. Ed. Eng., 2009, 48, 9493-7. Stephanopoulos, N., et al. “Nanoscale integration of sensitizing chromophores and porphyrins with bacteriophage MS2” Angew. Chem. Int. Ed. Engl. 2009, 48, 9498-502. Title: The Day the Dinosaurs Died Contact: Marjorie Leggitt Description: Mixed media editorial art created for the cover of the Denver Museum of Nature and Science Museum Quarterly magazine to illustrate an article on the sudden extinction of dinosaurs 65 million years ago. Although whimsical, the full time-lapse illustration (of which this is only half) represents a 15 million year span from before, during, and after the K-T boundary. Each animal, plant and reptile represents a particular individual or group of fauna and flora. Title: Influenza binding to sialic acids on host Contact: Mary O'Reilly Description: This illustration was created for a lecture on multivalency given to graduate students at the Freie Universitat in Berlin. Influenza viruses are coated with multiple copies of the sialic acid binding protein hemagglutinin, which binds to sialosides on cell surfaces in human airway epithelium, or avian gut epithelium, to invade the host. Title: Physical Therapy Excercise for Left Shoulder Contact: Ikumi Kayama Description: Pamphlet illustration describing the steps of physical therapy excercise after a shoulder injury. Title: Activity-based protein profiling Contact: Mary O'Reilly Description: This illustration describes a research program that aims to identify cysteine-reactive proteins and to decipher their biological functions using activity-based chemical probes, proteomics, and mass spectrometry. Title: the change Contact: Steven Melendrez Description: Photo retouching Title: Galectins with anti-bacterial activity Contact: Mary O'Reilly Description: Galectins are secreted glycan-binding proteins with numerous functions. A newly discovered function is to recognize and bind to blood group antigens on bacteria, which leads to destruction of the bacteria. This illustration was created to accompany a highlight for the March, 2010 Functional Glycomics Update (Nature Publishing Group) of the article by Stowell SR, et al. “Innate immune lectins kill bacteria expressing blood group antigen.” Nature Med. 2010 16, 295-301. Title: Journey to Africa Contact: Marjorie Leggitt Description: I designed, developed and illustrated this young audience flip book based on a poem written by an educator at the Denver Museum of Nature and Science. The flip book is used by teachers in the African Hall to illustrate different ecosystems and cultures. This is one of nine pages created entirely InDesign. Final size 24x18". Title: Spectacled flying fox Contact: Sarah Drummond Description: Pteropus conspicillatus, marker and photoshop image Title: Newly discovered DNA repair mechanism Contact: Mary O'Reilly Description: A mechanism for DNA repair has been discovered that combines elements of two known repair mechanisms. The protein Atl induces a base flipping similar to the demethylating enzyme Agt, but also invokes the nucleotide excision repair complex. This illustration was created to accompany a Scripps News&Views highlight of the paper by Tubbs JL, et al. “Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature, 2009, 459, 808-13. Title: Allergen-induced degranulation of mast cells Contact: Mary O'Reilly Description: Mast cells are decorated with cell surface Fc receptors that act as anchor and signal transducer for the IgE antibodies that are bound to them. Signals are only triggered when IgE antibodies are cross-linked, such as when mast cells encounter allergens (Pollen, ragweed, etc.). This binding and signal transduction leads to an allergic response, with a burst of histamine, cytokines, proteolytic enzymes, and other factors from the cell interior. Title: Mammoth Mixer Contact: Steven Melendrez Description: Title: Journey to Africa Contact: Marjorie Leggitt Description: I designed, developed and illustrated this young audience flip book based on a poem written by an educator at the Denver Museum of Nature and Science. The flip book is used by teachers in the African Hall to illustrate different ecosystems and cultures. This is one of nine pages created entirely InDesign. Final size 24x18". Title: Ladybug chasing Aphids Contact: Melisa Beveridge Description: Coccinellida and Hemiptera interaction on a pepper plant. Title: Restraint Contact: Lesley Sealing Description: A cartoon depicting restraint of a patient in a veterinary hospital Title: Eye Exam Contact: Lesley Sealing Description: A cartoon of a lady and her dog about to have an eye exam Title: Transgenic Zoomorph (Donkey/Elephant) Contact: Michael Rothman Description: This image is the result of a commission by the New York Times for its Week In Review section, prior to the 2000 U.S. Presidental election. The painting is composed of a Donkey and an Elephant ""welded" together anatomically. As such, this transgenic animal is really a deliberate chimera functioning as piece of editorial illustration. At the time, the author of the accompanying article made a number of assertions virtually equating the broad and overarching agendas of the two major American political parties. Interested individuals might disagree with the author's positions when they are examined through the lenses of 20/20 hindsight. Title: Glaucoma Contact: Lesley Sealing Description: A cartoon showing what happens to the eye when a person or animal has glaucoma Title: Singing House Wren Contact: Dorothia Rohner Description: This black and white drawing of a house wren, (Troglodytes aedon) was created for a collection of nature rubber stamps. Watercolor washes were added. Title: World Aquaculture Logo Contact: John Norton Description: Created for the World Aquaculture Society. Suitable for T-shirts and conference logos. Title: Monarch Butterfly Drawings Contact: Dorothia Rohner Description: Monarch butterfly designs created from original paintings and drawings. Used for stickers and rubber stamp designs. Title: Compy Contact: Steven Melendrez Description: Compsognathus, one the smallest dinosaurs. Title: Terell the T-Rex & Compy Contact: Steven Melendrez Description: T-Rex and Compy the largest and the smallest carnivorous dinosaurs Title: Iggy the Iguanodon Contact: Steven Melendrez Description: Iguanodon cartoon Title: Water Usage and Pollution Prevention Contact: John Norton Description: Title: Hands at Work Contact: Emil Huston Description: Various hands doing a variety of activities. Displaying images 1 to 64 of 87.